It can also cause panic and despair.

What could have happened to cause such panic and despair?

But all of this is causing despair among politicians and average citizens with centrist, secular or leftist views.

It destroys trust, causes despair, prevents people from loving, from living a full life.

Lovely song, but heard too early in the season it causes private despair instead of commercial elation.

The ship was then ordered to return to Europe, causing despair among the remaining passengers.

Some readers say that the ringwraiths couldn't cause such despair unless they themselves felt it.

For the sake of evil, the Slumlords twist the law to cause agony and despair.

It seemed that they were so far gone they had not seen the party until then, for Jim's voice caused confusion and despair among them.

Although their general lack of money caused despair, material welfare was a secondary consideration.