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Hxd3 is the only pure culture that is known to carboxylate aliphatic hydrocarbons.
Inverting enzymes utilize two enzymic residues, typically carboxylate residues, that act as acid and base respectively, as shown below for a β-glucosidase:
One example is the sandwich nanohybrid of SWNHs-TiO-porphyrin, prepared via the dentate binding of TiO nanoparticles to carboxylate groups.