It is more generally understood as pain that is made worse rather than better by increasing doses of morphine.

First, Ryoval would condition him to this, addict him by repeated doses.

Therefore, the clinician's fear of shortening life by increasing opioid doses is usually unfounded.

But they all had the poleaxed look of men kept awake by inadequate doses of stim.

But you do that by heavier doses of prevention.

Like a person used to large doses of a drug, I was uninfluenced by small doses.

But you do that by heavier doses of community policing.

We achieved this by minute doses of copper and carbo animalis.

Most of the party had malaria, and could be kept going only by large doses of quinine.