PA 157 begins at an intersection with US 62 in Cranberry Township, Venango County, heading south-southeast on a two-lane undivided road.

PA 390 begins at an intersection with PA 940 in Paradise Township, Monroe County, heading northeast on a two-lane undivided road.

PA 913 begins at an intersection with PA 26 in Liberty Township, Bedford County, heading east on a two-lane undivided road.

Route 24 begins at an interchange with Interstate 287 in Hanover Township, Morris County, heading southeast on a six-lane freeway.

PA 410 begins at an intersection with US 119 in Henderson Township, Jefferson County, heading east on a two-lane undivided road.

PA 240 begins at an intersection with PA 286 in Green Township, Indiana County, heading southeast on a two-lane undivided road.

PA 427 begins at an intersection with US 322 in Sugarcreek, Venango County, heading northwest on a two-lane undivided road.

PA 154 begins at an intersection with US 220 in Laporte Township, Sullivan County, heading northwest on a two-lane undivided road.

Loop 332 begins at an intersection with SH 29 in Liberty Hill, Williamson County, heading southeast on a two-lane undivided road.

PA 706 begins at an intersection with US 6 in Wyalusing, Bradford County, heading northeast on two-lane undivided Church Street.