Doctors say the shortage means that doses are reduced or becoming irregular.

And now her woman's courses had become so irregular, she did not even know if she was fertile any longer.

At first the cap is somewhat umbonate, later becoming irregular and flattened.

The whistling beeps of the frequency sensor had become irregular.

It was hard to understand why the floor had become so rugged and irregular.

By this point spelling had become quite irregular.

The wind had become violent and irregular; the balloon was running the gantlet through the air.

He sat by him for a few minutes more, monitoring his pulse, until Marshall's breathing became irregular, then stopped.

The man's breathing had become irregular, and his pallor had increased.