anti-citrullinated protein antibodies , ACPAs (Abkürzung)

The reference ranges for blood tests of anti-citrullinated protein antibodies are:

Because of this low specificity, new serological tests have been developed, which test for the presence of the anti-citrullinated protein antibodies (ACPAs) or anti-CCP.

Although the origin of this immune response is not known, detection of antibodies reactive with citrulline (anti-citrullinated protein antibodies) containing proteins or peptides is now becoming an important help in the diagnosis of rheumatoid arthritis.