He wrote an anguished letter to Mussolini, expressing his pain:

He shows an anguished letter signed by 11 nursing and retirement homes.

His anguished letters to several friends during the smallpox episode show that he cared desperately.

Rebecca has already written an anguished letter to Greg that is an invitation to a relationship.

Occasionally, when they knew the location of the cult, they tried to reach their loved ones with anguished letters.

Within two days there were 450 replies, many accompanied by despairing, anguished letters.

My friends were far away in London, they sent me anguished and reflective letters, what would they do now?

On the evening of December 5, she drafted an anguished letter to the President.

In the late 90's, she sent an anguished letter to her agent: "How much longer do I have to wait?"

She drafted a petition of protest and also published an anguished letter in the Guardian.