The problem of "control" in the aldol addition is best demonstrated by an example.

The product was named an aldol, pointing out its double character.

The combination of these two steps is known as the aldol condensation.

These first two steps are similar to a base-catalyzed aldol reaction.

The final step is a dehydration, as seen following an aldol condensation.

The aldol reaction may proceed via two fundamentally different mechanisms.

The product is the alkoxide salt of the aldol product.

Some unusual sugars are also accessible via aldol addition.

The aldol reaction is a very important reaction in organic chemistry.

The aldol reaction is powerful because it unites two relatively simple molecules into a more complex one.

One approach, demonstrated by Evans, is to silylate the aldol adduct.

Since the aldol addition reaction creates two new stereocenters, up to four stereoisomers may result.

This is the first example of an amino acid-catalyzed asymmetric aldol reaction.

These imines can be used to direct subsequent reactions like an aldol condensation.

However, reduction in the presence of an aldehyde leads to reductive aldol products.

It is a modification of the aldol condensation.

This enolate was reacted with 4-pentenal in an aldol reaction to give β-hydroxyketone 9.

Modern ways of doing the aldol reaction also allow to control the stereochemistry of the product.

The best example is the aldol reaction.

Upon subsequent removal of the auxiliary, the desired aldol stereoisomer is revealed.

Carbonyls also may be alkylated by enolates as in aldol reactions.

The reaction is classified as an Aldol condensation.

These products arise via an initial aldol condensation to give diacetone alcohol.

He has also developed novel methodology for organic synthesis such as a modification of the Evans aldol reaction.

The capture of the initial formed aldol product is a prerequisite for the success of the reaction.