It also affected the course of his career in practical terms.

Perhaps one day we both will have the power to affect the course of our two governments.

The southern mountains also affected the course of the river.

But it was really only a very small battle which did not affect the course of the war.

How 20th-century presidential marriages affected the course of American history.

However, the test in question does not affect the course of action as to what treatment should be done.

They also could ask if there were genes that affected the course of the disease.

Three to five weeks from today, somebody is going to be down there who could affect the course of the entire galaxy.

The right rhetorical style can still affect the course of events.

"I think this will affect the future course of the party's response."