The initial autopsy found that Hatfield had advanced coronary disease.

Most patients diagnosed with cubital tunnel syndrome have advanced disease (atrophy, static numbness, weakness) that might reflect permanent nerve damage that will not recover after surgery.

Chemotherapy has been combined with radiation therapy in patients who have locally advanced disease that is surgically unresectable.

In the Quebec study, in fact, four of the five deaths among the screened patients were from those who already had advanced disease by the time their first screening detected it.

The cause of death was presumed to be cancer related if the patient had advanced recurrent disease at the time of death.

The remaining patients (20%) had advanced disease, usually with liver metastases - that is, stage D, at the time of their initial surgery.

Compared to those who enrolled, those who declined were more likely to have advanced disease.

Forty-three of them had advanced disease at the time of diagnosis.

A study of the use of HIV services by 653 Asians and Pacific Islanders showed that a relatively high proportion had advanced disease and used hospital-based services.