It is also a sign of acute rejection after heart transplant surgery.

Until the routine use of medications to prevent and treat acute rejection, introduced in 1964, deceased donor transplantation was not performed.

Chronic rejection of the lungs differs significantly from acute rejection.

This is called acute rejection and occurs in 25% to 55% of people after transplant.

Most of the time, acute rejection can be treated with immunosuppressive medicines.

None of these recipients experienced acute rejection or any other side effects with this therapy.

But with no acute rejection, immediate therapy and amputation were not needed.

"The body went into acute rejection of the heart," Chavez said.

And as doctors learned how to use older drugs more effectively, they reduced deaths from acute rejection to a rarity instead of a common problem.

Effect of herbal supplements on cyclosporine blood levels and associated acute rejection.