It also has two active metabolites with half-lives of 28 and 79 hours.
Peak plasma concentrations of active metabolites 1 and 2 are reached after three to four hours.
Peak levels of the main active metabolite, diacetolol, are reached after 4 hours.
The active metabolites of heroin are morphine, 6-monoacetylmorphine and 3-monoacetylmorphine.
As in the previous case it is possible to find paradoxical situations where an active metabolite causes the drug's effect.
It has a long duration of action due to its active metabolites.
An active metabolite is an active form of a drug after it has been processed by the body.
The company's initial focus was on the development of single isomers and active metabolites.
Deacetylating vecuronium at position 3 results in a very active metabolite.
It may have additional active metabolites that contribute to its clinical activity.