About two hundred thousand tonnes of tetrahydrofuran are produced annually.

It is usually sold as a solution in tetrahydrofuran.

It is prepared by the reaction of 1,4-butanediol or tetrahydrofuran with hydrogen sulfide.

The latter is turned into tetrahydrofuran by action of a catalyst and then polymerized.

When prepared in this way, it is most often used without isolation as a solution in tetrahydrofuran.

It is a popular, but costlier substitute for tetrahydrofuran.

The compound is commercially available as a solution in tetrahydrofuran and as a solid.

It is also a component - along with tetrahydrofuran - of the solvent used to weld plumbing.

This page provides supplementary chemical data on tetrahydrofuran.

It is insoluble in alcohol, but slightly soluble in tetrahydrofuran.

The chemical result, in this case, is a disfavored reaction that produces tetrahydropyran instead of tetrahydrofuran.

A ring-opening reaction with hydrogen fluoride in tetrahydrofuran gives dexamethasone.

The reaction typically is carried out in tetrahydrofuran or diethyl ether as solvent.

It is related to tetrahydrofuran by interchange of one oxygen for a CH group.

In methanol it converts to the cyclic acetal, 2,5-dimethoxyl tetrahydrofuran.

Anhydrous ethyl ether or tetrahydrofuran would be good choices.

It can be viewed as a polymer of tetrahydrofuran, or as the polyether derived from 1,4-butanediol.

It is soluble in organic solvents tetrahydrofuran and hexane.

In tetrahydrofuran, it equilibrates between monomer and dimer states.

It reacts with acetone, ethyl acetate, tetrahydrofuran, ethanol, and water.

In many transition metal compounds, the empty coordination site is stabilized by a coordinating solvent like tetrahydrofuran.

Polytetrahydrofuran is commonly prepared by acid-catalyzed polymerization of tetrahydrofuran.

In the presence of phosphoric acid and high temperature, it dehydrates to the important solvent tetrahydrofuran.

Typically, such reactions are conducted with zinc amalgam in moist tetrahydrofuran:

In tetrahydrofuran, the mechanism of alkyl halide reduction likely proceeds through radical intermediates.

Folinic acid is a 5-formyl derivative of tetrahydrofolic acid.

Tetrahydrofolic acid, or tetrahydrofolate, is a folic acid derivative.

Trimethoprim acts by interfering with the action of bacterial dihydrofolate reductase, inhibiting synthesis of tetrahydrofolic acid.

Tetrahydrofolic acid is needed for DNA and RNA synthesis in many species, including protozoa.

Dihydrofolic acid (dihydrofolate, vitamin B) is a folic acid derivative which is converted to tetrahydrofolic acid by dihydrofolate reductase.

Pyrimethamine interferes with tetrahydrofolic acid synthesis from folic acid by inhibiting the enzyme dihydrofolate reductase (DHFR).

Trimethoprim binds to dihydrofolate reductase and inhibits the reduction of dihydrofolic acid (DHF) to tetrahydrofolic acid (THF).

This antagonistic effect is not due to the inhibition of dihydrofolate reductase, the enzyme responsible for the reduction of dihydrofolic acid to tetrahydrofolic acid, but rather to defective folate metabolism.

Folic acid, (tetrahydrofolic acid or the reduced form) in mega dosages of 80 mg/day is a competitive inhibitor that blocks the activity of XO (through XO's flavin active sites).

Tetrahydrofolic acid is an essential precursor in the de novo synthesis of the intermediate Thymidine monophosphate (dTMP), precursor of DNA metabolite Thymidine triphosphate.

Folic acid in the study was prepared as tetrahydrofolic acid or the reduced form in 20 mg tablets, formulated with an equal amount of ascorbic acid for antioxidant purposes and for better absorption through the gut.

Dihydrofolate reductase, or DHFR, is an enzyme that reduces dihydrofolic acid to tetrahydrofolic acid, using NADPH as electron donor, which can be converted to the kinds of tetrahydrofolate cofactors used in 1-carbon transfer chemistry.

Tetrahydrofolic acid is involved in the conversion of formiminoglutamic acid to glutamic acid; this may reduce the amount of histidine available for decarboxylation and protein synthesis, and hence the urinary histamine and formiminoglutamic acid may be decreased.

The simultaneous addition of sodium formate to such systems resulted in increased citrovorum factor activity in the cell-free supernatants (producing, as we know now, the 5-formyl derivative), and from this method of preparation of large amounts of the factor, its structure as levo-folinic acid (5-formyl tetrahydrofolic acid) was eventually deduced.