The Republicans will be struggling to hold a majority in the Senate, where they outnumber Democrats 19 to 17.
Republicans, meanwhile, are struggling to add provisions to their capital gains tax cut proposals that would benefit the middle class.
But there are enough of them, particularly in places where Republicans are struggling, to cast doubt on the party's long-standing strategy.
Throughout the Capitol these days, the Republicans are still struggling with the transition from broad principle to real-life policy.
Republicans who support abortion rights are struggling, once again, to change that language.
At a time when the Republicans are struggling to soften their image on environmental issues, the bill is one that many moderates would rather avoid altogether.
There are complex multi-strand reasons why the Republicans are struggling to find a solid candidate.
In the week leading up to the votes, Republican and Democratic leaders struggled to come up with a plan that all sides could accept.
It is hardly as if Republicans had struggled here before.
Still, the effort comes as Republicans are struggling to keep the moderate and conservative wings of the party together and functioning.