In the mid-1980s it was becoming clear that ribosomal RNA sequences could be used to determine metazoan relationships.
By convention, RNA sequences are written in a 5' to 3' direction.
Using comparative analysis, he also recognized the limitations that RNA sequences could provide when identifying closely related species.
The more alike their ribosomal RNA sequences, the more closely they are related.
The researchers inserted RNA sequences that also formed base paired structures.
Several RNA sequences have been identified that bind small molecules, like the drug tetracycline.
It's not much of a stretch to think that life started out with RNA sequences handling all information storage functions.
Assembling the 7741-base genome from scratch, starting with the virus's published RNA sequence, took about two years.
These are based on detecting a leukemic specific RNA sequence.
This process effectively changes the RNA sequence from that encoded by the genome and extends the diversity of the gene products.