He was perhaps the first (1882) to recognize angioedema which is often referred to as "Quincke's edema".

Skin allergic reactions: skin rash, hives, Quincke's edema, anaphylactic shock.

Related indications for clinical use include Quincke's edema, allergic reactions to insect bites, food and drug allergies, and anaphylactic shock.

People who are atopic may also have other medical problems including food and drug allergies, stinging-insect hypersensitivity, hives (urticaria), Quincke's edema (angioedema), and contact dermatitis.

Angioedema (BE: angiooedema) or Quincke's edema is the rapid swelling (edema) of the dermis, subcutaneous tissue, mucosa and submucosal tissues.

Anaphylactoid reactions such as shock, urticaria, and Quincke's oedema have been reported to generally appear within two hours after taking the first tablet.

Rarely, angioneurotic edema and decreases in hemoglobin, red cells, and platelets have been reported.

Hepatic microsomal enzyme induction, altered lacrimation, menorrhagia, hyperkinesia, hypoesthesia and angioneurotic edema.

Deficiency of this protein is associated with hereditary angioedema ("hereditary angioneurotic edema"), or swelling due to leakage of fluid from blood vessels into connective tissue.

Furthermore the mechanism of focal infection theory survived in general medicine with regards to specific diseases such as tuberculosis, gonorrhea, syphilis, pneumonia, typhoid fever, and mumps as well as conditions such as idiopathic scrotal gangrene and angioneurotic edema.