After some familiarity and training missions, the 19th conducted its first B-29 bombing raid over Japan on 25 February 1945, attacking Northeast Tokyo on a high-altitude bombing mission.

The squadron began combat missions over Japan on 25 February 1945 with a firebombing mission over Northeast Tokyo.

The 19th began combat missions over Japan on 25 February 1945 with a firebombing mission over Northeast Tokyo; the 29th with a firebombing mission over central Tokyo on March 9.