The 13th-seeded Lady Pirates (19-14) struggled early in the season but had won their previous 10 games.
Cherie Mills kept the Lady Pirates in the game with solid inside play.
The Lady Pirates scored 168 points, followed by St. John's with 134 and Manhattan with 108.
The Lady Pirates are led by second year head coach Heather Macy who led the team to a 19-16 record in her first season at the helm.
From 2007-2010 the Lady Pirates have posted three consecutive winning seasons.
In 2011, as a number-13 seed, the Lady Pirates nearly upset Kentucky, but fell in overtime, 66-62.
The Lady Pirates have won 9 of their last 10 games.
The Lady Pirates became the most prolific women's team ever in the sport.
The Lady Pirates' final average dropped to 99.1 after five tournament games.
The Lady Pirates have won 20 games six times and have made it to the national quarterfinals four years in a row, including two trips to the semifinals.