His work was the subject of a 1979 monograph, Monsters of the Gilded Age, focusing on his work on human oddities from the Barnum and Bailey circus, with a notable widely circulated picture of Jojo the Dog-faced Boy.

A number of Eisenmann's favorite subjects can be seen depicted in the The X-Files episode "Humbug", namely Jojo the Dog-faced Boy and Chang and Eng Bunker.

See Hando the Dog-Faced Boy, terror of the South Seas!

Somewhat inauspiciously, he scored his first film role as Duke the Dog-Faced Boy, a circus performer, in the Pee-Wee Herman film "Big Top Pee-wee" (1988).

The band Phish has a song called "Dog-Faced Boy"

But let's be honest: who among us has not slipped into the carnival tent to take a peek at Jo-Jo the Dog-Faced Boy?

Sort of the way you'd look at the bearded lady or Jo-Jo the Dog-Faced Boy, if you met them on the street rather than in a sideshow: a mixture of fear, apprehension, and pity.

He was a part of the second Daredevil's circus as the Dog-Faced Boy before joining the X-Men.

So off to see the Fat Lady, the Dog-faced Boy, or whatever exotic creatures might infest Boca Blanca's version of the Big Top.