This was the first known enzyme to take its instructions from a DNA copy.
It means having two RNA genome per virion but giving rise to only one DNA copy in infected cells.
RNA is used as the target and a DNA copy is made.
The DNA copy is then transcribed into RNA and amplified.
The disadvantage is that there is no 'back-up' DNA copy.
The fact that DNA copy number variation is a widespread and common phenomenon among humans was first uncovered following the completion of the human genome project.
Without a bacterial host it can't reproduce, but neither can DNA copy itself without a cell's chemical machinery.
The DNA copy is then inserted into the genome in a new position.
Secondly, it could bind to the DNA copy of the viral RNA.
A provirus does not directly make new DNA copies of itself while integrated into a host genome in this way.