Clay Center was laid out in the summer of 1879.

In February 1887 Clay Center became an incorporated village.

Clay Center is located near several post-secondary institutions.

The novel, Clay Center by Phil Condon, was named after the town.

It goes east out of Clay Center into farmland until Geneva.

Miller was born and raised in Clay Center, Nebraska.

As of 2004, a family member's obituary reported he was still living in Clay Center, Kansas.

East on 24 is Wamego, west is Clay Center.

Clay Center can refer to a community in the United States:

It was first found in 1992 in a barley breeding nursery near Clay Center, Nebraska.