Michigan has now won 30 of its last 31 Big Ten openers, including its last seven.
It was the first time Illinois had lost consecutive Big Ten openers since 1908 and 1909.
Kansas State (0-5) lost its 10th consecutive game in the Big Eight opener for both teams.
In their Big Ten opener on homecoming, Purdue jumped all over Illinois early and often in a 43-10 win that brought them to a 4-1 mark.
The obvious answer would be that they were on the front end of a 45-24 score in the teams' Big Ten opener.
Iowa recovered from the tie with Air Force by crushing usually weak Indiana in both teams' Big Ten opener, 34-13.
The Bears have never won a Big 12 opener away game, nor have they won at Kyle Field since a 20-16 victory in 1984.
The game marked the Big Ten opener for both teams.
The Big 12 opener for both teams proved to be a tuneup for the Longhorns.
The Illini (3-1, 0-1) have not won a Big Ten opener since 1993.