As an option to WU-BLAST, Gish implemented a faster, more memory-efficient and more sensitive two-hit BLAST algorithm than is used by the NCBI software.
The services include PubMed, the bibliographic database; GenBank, the nucleotide sequence database; and the BLAST algorithm for sequence comparison, among many others.
Most notably, Altschul is the co-author of the BLAST algorithm used for sequence analysis of proteins and nucleotides.
Therefore, the BLAST algorithm uses a heuristic approach that is less accurate than the Smith-Waterman algorithm but over 50 times faster.
TimeLogic offers another FPGA-accelerated implementation of the BLAST algorithm called Tera-BLAST.
Later, the BLAST algorithm was developed for performing fast, optimized searches of gene sequence databases.
AAT is a local alignment software which extended the BLAST algorithm by assigning fixed penalty to long gaps [ 24 ] .
Sequences that failed to show significant homologies were used to query the GenBank (minus EST and BAC ends) database using the BLAST algorithms.
Each masked file was sent to the blastc13 server as a query for searching the dbEST database using the BLAST algorithm [ 45 ] .
Database search with these nucleotide sequences using the BLAST algorithm revealed many known positive or negative regulators of angiogenesis, including proteases and cell surface receptors.