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Zymosan is a ligand found on the surface of fungi, like yeast.
Zymosan is prepared from yeast cell wall and consists of protein-carbohydrate complexes.
Zymosan is a glucan with repeating glucose units connected by β-1,3-glycosidic linkages.
Zymosan A also raises cyclin D2 levels suggesting a role for the latter in macrophage activation besides proliferation.
Also studies using the mouse zymosan model and chemerin peptides showed that these peptides suppressed and helped resolve the peritonitis in mice.
When an agent, zymosan, was injected into the tunicate Styela plicata (causing inflammation), secretion of this collectin was tripled within 96 hours.
Stefanova Z, Neychev H, Ivanovska N, Kostova I. Effect of a total extract from Fraxinus ornus stem bark and esculin on zymosan- and carrageenan-induced paw oedema in mice.