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This disease causes the zonular fibres to be abnormal and begin to disintegrate in affected dogs.
In cartilaginous fish, the zonular fibres are replaced by a membrane, including a small muscle at the underside of the lens.
In reptiles and birds, the ciliary body touches the lens with a number of pads on its inner surface, in addition to the zonular fibres.
These pads compress and release the lens to modify its shape while focusing on objects at different distances; the zonular fibres perform this function in mammals.
The shape of the lens can be altered by ciliary muscles which are directly attached to lens capsule by means of the zonular fibres.
The white fluffy material is seen in many tissues both ocular and extraocular: in the anterior chamber structures, trabecular meshwork, central disc, zonular fibres, anterior hyaloid membrane, pupillary and anterior iris, trabecula, and occasionally the cornea.