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Other findings show connexins associate with protein scaffolds used in another junction, the zonula occludens ZO1.
Tight junctions, or zonula occludens, are the closely associated areas of two cells whose membranes join together forming a virtually impermeable barrier to fluid.
Our results support the hypothesis of a functional alteration in the zonula occludens in the intestinal epithelium of coeliac patients.
The second non-CT toxin encoded within the CTXφ genome is zonula occludens toxin (Zot).
In males, FSH induces Sertoli cells to secrete inhibin and stimulates the formation of sertoli-sertoli tight junctions (zonula occludens).
An in vivo uptake of polypeptides by the human enterocytes has not been demonstrated previously, and the zonula occludens (tight junction) between the cells is usually considered impermeable to macromolecules in man under physiological conditions.
Initially discovered in 2000 as the target of zonula occludens toxin, secreted by cholera pathogen Vibrio cholerae, it has been implicated in the pathogenesis of coeliac disease and diabetes mellitus type 1.
Terminal bar is a histological term given to the unresolved group of junctional complexes that attach adjacent epithelial cells on their lateral surfaces: the Zonula Occludens, Zonula Adherens, Macula Adherens and Macula Communicans.