If there are problems, I think they will be in the area of false negatives.
When a disease is rare, false negatives will not be a major problem with the test.
About 39% of the related documents will be rejected; these are the false negatives.
This approach is good in terms of speed but poor with regard to false negatives and sensitivity.
Patients that receive false negatives are unlikely to seek further treatment for their disease.
Similarly, the use of certain substances, such as steroids may lead to false negatives.
"But the search for false negatives is difficult, cumbersome and expensive."
Therefore, the number of true positives increase and false negatives decrease.
Moreover, we have seen that, at certain times, the tests involve risks because they produce false negatives.
Skin prick tests are not always accurate and may produce false negatives.
Even a small increase in fluorescent efficiency could reduce background noise and lower the rate of false-negative results.
Exfoliative cytology has a high number of false-negative results.
Focusing on older L1 family members is likely to increase the rate of false-negative results.
Do not wash before the test, because that may cause a false-negative result.
But the culture often fails to find the virus even when it is present (false-negative results).
But these tests sometimes give false-positive or false-negative results.
A false-negative result from a blood test is possible if you have been infected recently.
Failure to detect T. pallidum does not definitively rule out infection because false-negative results are common.
Therefore they may be undetected by corresponding diagnostic tests and gave a false-negative result for the infection.
However, regular screening helps to compensate for false-negative results.