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He held the wardenry until October 1595, when he was superseded by Lord Eure; his removal was due partly to his old age, partly to a renewal of the charges against him.
In spite of advancing years, Wharton retained his wardenry throughout Mary's reign, the Earl of Northumberland being joined with him on 1 August 1557 when fresh trouble with the Scots was imminent (owing to the war with France).