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Warty dyskeratoma must be differentiated from vulvar dysplasia, bowenoid papulosis, squamous carcinoma, condyloma, and other viral-induced squamous lesions.
Usually performed as a last resort in certain cases of cancer, vulvar dysplasia, Human Papilloma Virus or FGM/C (genital Mutilation).
If treatment of vulvitis does not work, further evaluation may include biopsy of the skin to rule out the potential of vulvar dystrophy (a chronic vulvar skin condition) or vulvar dysplasia, a precancerous condition.