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From the 1860s the concept of unitary psychosis and its advocates came under increasing criticism.
He would become perhaps the figure most associated with the concept of unitary psychosis in German psychiatry.
While there, he adopted and adapted his senior colleague's model of a unitary psychosis.
Greisinger maintained his belief in unitary psychosis until the 1860s.
Variations of the unitary psychosis thesis have been revived occasionally during the 20th century.
This gave rise to the psychiatric doctrine of unitary psychosis which was highly influential in German psychiatry from the mid-nineteenth century.
The concept of unitary psychosis is ultimately derived from the work of the Belgian psychiatrist Joseph Guislain (1797-1860).
The greatest defender and the most radical proponent of the concept of unitary psychosis in the 19th century was the German psychiatrist Heinrich Neumann (1814-88).
Eysenck's theoretical basis for the model was the theory of Einheitspsychosen (unitary psychosis) of the nineteenth-century German psychiatrist Heinrich Neumann.
The dominant psychiatric paradigms which gave a semblance of order to this fragmentary picture were Morelian degeneration theory and the concept of "unitary psychosis" (Einheitspsychose).
Conrad, a proponent of Gestalt psychology, is typically characterised as having expounded a view of psychosis that is commensurate with the mid-19th century psychiatric concept of unitary psychosis.
Unitary psychosis (Einheitspsychose) refers to the 19th-century belief prevalent in German psychiatry until the era of Emil Kraepelin that all forms of psychosis were surface variations of a single underlying disease process.
The pioneering research of Kahlbaum and Hecker proposed the existence of more than one discrete psychiatric disorder, which contrasted with the concept of "unitary psychosis" that maintained all psychiatric symptoms were manifestations of a single mental disorder.
During his inaugural lecture following his appointment to the chair of psychiatry in Dorpat University in 1887, Kraepelin contended that Zeller's notion of unitary psychosis had led to the calcification of clinical research in Germany until as late as the 1860s.
In the late 19th and early 20th centuries, terms such as "madness," "lunacy" or "insanity" - all of which assumed a unitary psychosis - were split into numerous "mental diseases," of which Catatonia, Melancholia and Dementia Praecox (modern day Schizophrenia) were the most common in psychiatric institutions.
In the modern era the concept of schizoaffective psychosis, which straddles the Kraepelinian divide, when delineated as a condition sharing a common causal pathway as both schizophrenia and affective psychosis, shares aspects of the more radical notion of unitary psychosis in regarding the individual psychoses as points on a continuum.