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Type I cells can be further divided by where the cell body or soma is located.
Type I cells are thinly shaped, usually in the periphery of other cells.
In contrast to Type I cells, they are unipolar and unmyelinated in most mammals.
Apoptosis (Type I cell death)
Type II cells have prominent nuclei and nucleoli with much less chromatin than Type I cells.
In the event of damage, Type II cells can proliferate and/or differentiate into type I cells to compensate.
In Type I cells, GFP-COP1 is expressed mostly in the cytoplasm, with some enrichment around the nucleus (Fig 3C, Type I).
These structures include the type I cells of the carotid body, the neuroepithelial bodies of the lungs as well as some central and peripheral neurons and vascular smooth muscle cells.
Type I cells have normal levels of CD55 and CD59; type II have reduced levels; and type III have absent levels.
Approximately 98% of alveolar wall surface area is due to the presence of type I cells, with type II cells producing pulmonary surfactant covering around 2% of the alveolar walls.
Vestibular afferent signals are carried by type I or type II hair cells, which are distinguished by a larger amount of stereocilia per cell in type I cells than in type II cells.