tunica media

Tunica media is made up of smooth muscle cells and elastic tissue.

The most striking histopathological changes of aneurysmatic aorta are seen in tunica media and intima.

Smooth muscle cells in the tunica media of many blood vessels also produce IL-6 as a pro-inflammatory cytokine.

The main chemical responsible is β-Aminopropionitrile, which prevents collagen cross-linking, thus making the blood vessel, especially the tunica media, weak.

The tunica media may (especially in arteries) be rich in vascular smooth muscle, which controls the caliber of the vessel.

It separates tunica intima from tunica media.

Within the tunica media, smooth muscle and the extracellular matrix are quantitatively the largest components of the aortic vascular wall.

It is characterized by fibrosis of the tunica intima and calcification of the tunica media.

They differ from other blood vessels in that they lack a full set of vessel layers (e.g. tunica media) characteristic of arteries and veins.

There is also smooth muscle proliferation and migration from the tunica media into the intima responding to cytokines secreted by damaged endothelial cells.

Deeper are bands of smooth muscle called tunica media, which are, in general, thin, as veins do not function primarily in a contractile manner.

Characterized by calcification of the Tunica media but without thickening of the intima or narrowing of the vessel lumen.

AAS can be caused by a lesion on the wall of the aorta that involves the tunica media, often in the descending aorta.

The vascular wall consists of several layers known as the tunica adventitia, tunica media, and tunica intima.

However, the degradation of tunica media by means of proteolytic process seems to be the basic pathophysiologic mechanism of the AAA development.

This causes dilation of the "normal" segments of arteries; i.e. where the endothelium is not separated from the tunica media by atherosclerotic plaque.

These small vessels serve to provide blood supply and nourishment for tunica adventitia and outer parts of tunica media of large vessels.

The middle coat (tunica media) is distinguished from the inner (tunica intima) by its color and by the transverse arrangement of its fibers.

Vasodilation works to decrease TPR and blood pressure through relaxation of smooth muscle cells in the tunica media layer of large arteries and smaller arterioles.

A tear in vasa vasorum situated in tunica media layer of aorta may start pathologic cascade of events leading to aortic dissection.

The tunica externa, also known as the tunica adventitia (or adventitia), is the outermost layer of a blood vessel, surrounding the tunica media.

Within the tunica media, smooth muscle fibers were organized so that the long axis of the cells ran at an angle to circular axis of the vessel wall (Fig.

Most are true aneurysms that involve all three layers (tunica intima, tunica media and tunica adventitia), and are generally asymptomatic before rupture.

In arteries and veins the inner wall is the tunica intima, the outer wall is the tunica adventitia, and they are separated by the tunica media.

Instead of a continuous tunica media, they have individual smooth muscle cells placed a short distance apart, each forming a precapillary sphincter that encircles the entrance to that capillary bed.