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Tufted cells are found within the olfactory glomeruli.
They have inhibitory synapses on mitral cells and tufted cells.
EPSPs are amplified by persistent sodium ion conductance in external tufted cells.
After the processing in the bulb the signal is transmitted caudally via the axons of mitral and tufted cells in the lateral olfactory tract.
GABA is responsible for much of the work of the IPSPs in the external tufted cells.
Each glomerulus is surrounded by a heterogeneous population of juxtaglomerular neurons (that include periglomerular, short axon, and external tufted cells) and glial cells.
IPSPs come into the picture when the tufted cells membranes are depolarized and IPSPs then cause inhibition.
As with the visual system, in mitral/tufted cells in the olfactory bulb of mice, first-spike latency relative to the start of a sniffing action seemed to encode much of the information about an odor.
There are also in the plexiform layer GABAergic synaptic connections between the apical dendrites of granular cells and the basal dendrites of the tufted cells and mitral cells.
The olfactory tract is a bundle of axons connecting the mitral and tufted cells of the olfactory bulb to several target regions in the brain, including piriform cortex, amygdala, and entorhinal cortex.
The glomerulus (plural glomeruli) is a spherical structure located in the olfactory bulb of the brain where synapses form between the terminals of the olfactory nerve and the dendrites of mitral, periglomerular and tufted cells.