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For example, troponin T mutations are associated with a 50% mortality before the age of 40.
Troponin T is a part of the troponin complex.
Troponin T binds to tropomyosin and helps position it on actin.
Cardiac troponin T and I are measured by immunoassay methods.
He developed the troponin T assay.
High troponin T levels have also been reported in patients with inflammatory muscle diseases such as polymyositis or dermatomyositis.
Patients with end-stage renal disease can have chronically elevated troponin T levels, which are linked to a poorer prognosis.
This prognostic information was independent of troponin T, ECG and clinical examination.
Cardiac troponin T and I can be used to monitor drug and toxin induced cardiomyocyte toxicity.
Fetal Troponin T and Troponin I isoforms.
Troponin T, slow skeletal muscle is a protein that in humans is encoded by the TNNT1 gene.
"Value of qualitative troponin T estimation in decision making in patients with chest pain" in The British Journal of Cardiology, 1998.
H-FABP is more effective than Troponin T in risk stratifying Chronic Heart Failure patients.
Blood tests for measuring elevated enzymes in the blood, including cardiac-specific troponin T and/or troponin I, myoglobins, and creatine kinase isoenzymes.
There are other protein molecules bound to the tropomyosin thread, these are the troponins that have three polymers: troponin I, troponin T and troponin C.
In patients with stable coronary artery disease, troponin T concentrations have been found to be significantly associated with the incidence of cardiovascular death and heart failure, but not with myocardial infarction.
Lipshultz SE, Rifai N, Sallan SE, et al.: Predictive value of cardiac troponin T in pediatric patients at risk for myocardial injury.
Heart muscle injury characterized by elevated levels of CK-MB, troponin I, and troponin T may occur in up to 30% of all PCI procedures.
Alongside D-dimer, NT-proBNP and peak troponin T, it was the only cardiac biomarker that proved to be a statistically significant predictor of death or Mi at one year.
Heeschen C, Goldmann BU, Terres W, et al.: Cardiovascular risk and therapeutic benefit of coronary interventions for patients with unstable angina according to the troponin T status.
Herman EH, Zhang J, Rifai N, et al.: The use of serum levels of cardiac troponin T to compare the protective activity of dexrazoxane against doxorubicin- and mitoxantrone-induced cardiotoxicity.
Troponin is a complex of three regulatory proteins (troponin C, troponin I and troponin T) that is integral to muscle contraction in skeletal and cardiac muscle, but not smooth muscle.
The existence of putative tissue-specific splicing factors in muscle cells has gained support particularly through work on such genes as α-tropomyosin (19) and troponin T (20) which are known to produce tissue-specific and developmentally regulated isoforms.
Troponin I and troponin T CPK and CPK-MB Serum myoglobin If you had a heart attack, you will need to stay in the hospital, possibly in the intensive care unit (ICU).
Under normal circumstances, the tropomyosin sterically obstructs binding sites for myosin on the thin filament; once calcium binds to the troponin C and causes an allosteric change in the troponin protein, troponin T allows tropomyosin to move, unblocking the binding sites.