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In most cases, Trichorhinophalangeal syndrome type I has autosomal dominant inheritance.
Hyperdontia is often associated with syndromes such as cleft lip and palate, trichorhinophalangeal syndrome, cleidocranial dysplasia, and Gardner's syndrome.
Differential diagnoses include velocardiofacial syndrome (Shprintzen syndrome), trichorhinophalangeal syndrome, De Lange syndrome, Rubinstein-Taybi syndrome and monosomy 22q11.
TRP Syndrome TRPS1 None Trichorhinophalangeal syndrome type I (TRPS1) is an extremely rare inherited multisystem disorder.