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However, the rate of treatment discontinuation due to nausea was not significantly different.
If severe, dose adjustment or treatment discontinuation may be required.
Early treatment discontinuation was occurring far too frequently and eventually resulted in negative effects on several patients.
The patient was admitted to hospital the next day, and died eight days later, the final diagnosis being "acute heart failure due to treatment discontinuation".
No dosage tapering is needed on treatment discontinuation.
Adverse effects of interferon-alfa use in children, although frequent, usually are not severe or permanent; however, approximately 5% of children require treatment discontinuation.
However, treatment for ocular microsporidiosis should be continued indefinitely because recurrence or relapse might follow treatment discontinuation (BIII).
The most common side effects seen with the medical use of FAE are gastro-intestinal symptoms and flushing, which can be the cause of treatment discontinuation in some patients.
Lymphocyte proliferative response to recombinant HIV-1 p24 protein had to exceed a stimulation index of ten before treatment discontinuation, and net counts per minute had to be 800 or greater.
For HBeAg-negative patients with increased ALT and HBV DNA levels, long-term antiviral suppression might be indicated because treatment discontinuation has been associated with virologic relapse.
The recent EMA evaluation also revealed high potential for Parkinsonian (or extrapyramidal) symptoms (such as tremor, rigidity, akinesia, hypertonia), gait instability, restless leg syndrome, other related movement disorders, reversible after treatment discontinuation.
"In randomized controlled trials, bradycardia was reported more frequently in galantamine-treated patients than in placebo-treated patients, but was rarely severe and rarely led to treatment discontinuation" These side effects have not been reported in Alzheimer's Disease related studies.
Other studies of RTV-boosted APV regimens have also reported that triglyceride elevation is usually grade 1 or 2 in magnitude, and, as in the present study, seldom necessitates treatment discontinuation or the addition of antihyperlipidemic drugs to the patient's treatment plan [ 10 19 ] .