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Reliable, toxicologically proven limit values make sense, rush jobs and thrashing about in the dark do not.
If these arbitrary and toxicologically unjustified residue levels were observed, fruit and vegetables could no longer be produced by conventional means.
In the journal Science in 1990, two agency scientists concluded that "no toxicologically significant changes" were seen in rats that ingested the hormone.
Calandra, the first of his family to pursue higher education, contributed to the concept of toxicologically innocuous doses during his tenure at Northwestern.
Rollin quotes F. Sperling, whose conclusion is even more abrupt: 'The LD50 is in fact only marginally informative, toxicologically inadequate, and misleading'(1981: 98).
The tightening of the rules, the shortening of the deadlines and the inclusion of mercury compounds in the export and import provisions are both appropriate and toxicologically consistent.
To compare the toxicities of various congeners and to render it possible to make a toxicologically meaningful sum of a mixture, a toxicity equivalency (TEQ) concept was created.
Toxicology studies in New Zealand White rabbits (3 weekly i.v. doses of 10 PFU) showed that JX-594 was well tolerated, and no toxicologically significant effects were observed.
Sometimes these by-products are detectable by odor, in which case they are referred to as "ergonomic odors" meaning the odors are detectable, but do not indicate toxicologically significant exposures.
This resembles the common measure of all alcoholic drinks: beer, wine and whiskey can be added together as absolute alcohol, and this sum gives the toxicologically meaningful measure of the total impact.
This multiplication is done for all compounds in a mixture, and these "equivalents of TCDD" can then simply be added, resulting in TEQ, the amount or concentration of TCDD toxicologically equivalent to the mixture.
It is one of the dominant dioxin congeners in smoke emissions, but because it is much less soluble than e.g. TCDD, it is not bioaccumulated as effectively and it is toxicologically less important than the most prevalent dioxins (for details see Dioxins and dioxin-like compounds).
He also said that there was a "statistically significant" cluster of birth defects between 1989 and 1999, and that, "toxicologically, there were present on and from the Corby Borough Council sites, over the whole period from 1985 (and possibly before) until 1997, the types of contaminants which could cause the birth defects complained of."