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Mutations in this gene have been linked to thyrotoxic periodic paralysis.
In a smaller number of cases, thyrotoxic crisis caused the body to simply shut down due to hormonal imbalances.
Thyrotoxic hypokalaemic periodic paralysis has been linked to altered K2.6 function.
An acute thyrotoxic encephalopathy is very rare.
This entity is distinguished with thyroid function tests, and the diagnosis is instead called thyrotoxic periodic paralysis.
Kazakov VM (Differential-diagnosis of thyrotoxic myopathy.
Thyrotoxic myopathy (TM) is a neuromuscular disorder that develops due to the overproduction of the thyroid hormone thyroxine.
Quinn EL, Worcester RL (Chronic thyrotoxic myopathy - report of a case.
Kazakov V (Pathogenesis of thyrotoxic myopathy (TM): On the hypothesis of muscle weakness origin, once again.
Nikolai Velyaminov described a new form of arthropathy (thyrotoxic polyarthritis) and developed a classification of diseases of the joints and thyroid gland.
Thyrotoxic crisis (or thyroid storm) is a rare but severe complication of hyperthyroidism, which may occur when a thyrotoxic patient becomes very sick or physically stressed.
Blood tests may be performed to exclude other causes of muscle disease (elevated creatine kinase may indicate a myositis, and abnormal thyroid function tests may indicate thyrotoxic myopathy).
The symptoms of periodic paralysis can also be caused by hyperthyroidism, and are then labeled thyrotoxic periodic paralysis; however, if this is the underlying condition there are likely to be other characteristic manifestations, enabling a correct diagnosis.
For example, a nodule that is overactive ("hot") to the point of suppressing the activity of the rest of the gland is usually a thyrotoxic adenoma, a surgically curable form of hyperthyroidism that is hardly ever malignant.