thyroid peroxidase

Thyroid peroxidase activity depends on iron; therefore, iron deficiency could lead to hypothyroidism.

Other foods containing genistein have been implicated as interfering with thyroid peroxidase in laboratory rats.

Thyroid peroxidase is the enzyme catalyzing the biosynthesis of the important thyroid hormones.

Thiouracil inhibits thyroid activity by blocking the enzyme thyroid peroxidase.

Selenium supplementation in patients with autoimmune thyroiditis decreases thyroid peroxidase antibodies concentrations.

DIT is a modulator of thyroid peroxidase.

However, millets are also a mild thyroid peroxidase inhibitor and probably should not be consumed in great quantities by those with thyroid disease.

Goitrogenicity of millet flavones : Vitexin inhibits thyroid peroxidase thus contributing to goiter.

Physiologically, antibodies to thyroid peroxidase and/or thyroglobulin cause gradual destruction of follicles in the thyroid gland.

Even maternal thyroid peroxidase antibodies were shown to be associated with impaired intellectual development in the offspring of mothers with normal thyroid function.

The chemical reactions catalyzed by thyroid peroxidase occur on the outer apical membrane surface and are mediated by hydrogen peroxide.

Various autoantibodies may be present against thyroid peroxidase, thyroglobulin and TSH receptors, although a small percentage of patients may have none of these antibodies present.

In thyroid cell differentiation FoxE binds to compacted chromatin of the thyroid peroxidase promoter and opens it for NF1 binding.

One MIT and one DIT are enzymatically coupled to form T. The enzyme is thyroid peroxidase.

We found that women with premature ovarian failure are significantly more likely to have positive thyroid peroxidase and parietal cell autoantibodies than women with normal ovarian function.

Heme l is the derivative of heme B which is covalently attached to the protein of lactoperoxidase, eosinophil peroxidase, and thyroid peroxidase.

Anti-TPO antibodies: In autoimmune thyroid disease, proteins mistakenly attack the thyroid peroxidase enzyme, which is used by the thyroid to make thyroid hormones.

Bonfig W, Gartner R, Schmidt H. Selenium supplementation does not decrease thyroid peroxidase antibody concentration in children and adolescents with autoimmune thyroiditis.

Thyroid peroxidase is a frequent epitope of autoantibodies in autoimmune thyroid disease, with such antibodies being called anti-thyroid peroxidase antibodies (anti-TPO antibodies).

Thioamides inhibit the enzyme thyroid peroxidase in the thyroid, reducing the synthesis of triiodothyronine (T3) and thyroxine (T4), thereby blocking uptake of iodotyrosines from the colloid.

Methimazole prevents the thyroid peroxidase enzyme from coupling and iodinating the tyrosine residues on thyroglobulin, hence reducing the production of the thyroid hormones T3 and T4 (thyroxine).

Antithyroid peroxidase (anti-TPO) binding activity was determined by a radiobinding assay using Iodine 125labelled human recombinant thyroid peroxidase (Nichols Institute, San Juan Capistano, CA).

The Wolff-Chaikoff effect lasts several days (around 10 days), after which it is followed by an "escape phenomenon", which is described by resumption of normal organification of iodine and normal thyroid peroxidase function.

Dr. Maloof was best known for his work on thyroid peroxidase, the enzyme that controls the production of thyroid hormone, and on the regulation of T.S.H., the hormone that controls the thyroid gland itself.

Once inside the follicular cells, the iodide diffuses to the apical membrane, where it is metabolically oxidized through the action of thyroid peroxidase to iodinium (I) which in turn iodinates tyrosine residues of the thyroglobulin proteins in the follicle colloid.