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These cells contain secretory granules which are thought to contain the thymic hormones.
Zinc is essential to the production of thymic hormones, needed to foster maturation of immune cells.
These cells produce Thymic hormones that cause T Lymphocytes to mature and differentiate.
However they are not truly thymic hormones in that they are not restricted in occurrence to thymus and several are widely distributed throughout many different tissues.
In addition to his work in transplantation, in the earlier part of his career he made several contributions to the development of prosthetic vascular grafts and the development and studies of biologic function of thymic hormones, both experimentally and clinically.