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A full medical dose of Thiopental reaches the brain in about 30 seconds.
The manufacturer of sodium thiopental stated that new supplies would not be available until 2011.
The subsequent nationwide shortage of sodium thiopental led states to seek for other drugs.
As a result of drug shortages, sodium thiopental was replaced by pentobarbital in 2011.
Sodium thiopental is used intravenously for the purposes of euthanasia.
Then, a dose of sodium thiopental puts you comfortably to sleep, as if you were going under for surgery.
Sodium thiopental is a short-acting barbiturate that must be administered in very controlled doses.
Also, they argue that the dose of sodium thiopental must be customized to each individual patient, not restricted to a set protocol.
Sodium thiopental is an anesthetic discovered by Abbott Laboratories in the 1930s.
Usually the sedative sodium thiopental is intravenously administered to induce a coma.
In veterinary medicine, sodium thiopental is used to induce anesthesia in animals.
In addition to anesthesia induction, sodium thiopental was historically used to induce medical comas.
Sodium thiopental is an ultra-short-acting barbiturate and has been used commonly in the induction phase of general anesthesia.
Co-administration of pentoxifylline and sodium thiopental may cause death by acute pulmonary edema in rats.
Thiopental is an ultra-short acting barbiturate that is marketed under the name sodium pentothal.
One problem with the combination of chemicals, Dr. Heath said in an interview, is that the sodium thiopental could be inadequate or wear off.
Thiopental (Pentothal) is still used in some places as a truth serum to weaken the resolve of the subject and make them more compliant to pressure.
Thiopental is famously associated with a number of anesthetic deaths in victims of the attack on Pearl Harbor.
Intravenous administration of sodium thiopental is followed instantly by an odor and/or taste sensation, sometimes described as being similar to rotting onions, or to garlic.
Thiopental reaches the brain within seconds and attains a peak brain concentration of about 60% of the total dose in about 30 seconds.
Thiopental is a rapid and effective drug for inducing unconsciousness, since it causes loss of consciousness upon one circulation through the brain due to its high lipophilicity.
After sodium thiopental began being used in executions, Hospira, the only American company that made the drug, stopped manufacturing it due to its use in executions.
Sodium thiopental is used to induce unconsciousness, pancuronium bromide (Pavulon) to cause muscle paralysis and respiratory arrest, and potassium chloride to stop the heart.
It also provides for a secondary fail-safe measure using intramuscular injection of midazolam and hydromorphone in the event intravenous administration of the sodium thiopental proves problematic.