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Elderly patients were also less likely to respond to therapy and had poorer survival outcomes.
This new information is providing the evidence we need to drive rapid improvement in cancer prevention, treatment, care and ultimately, survival outcomes.
Other regimens that appear to produce similar survival outcomes but are in less common use include:
Clinical evidence supports positive survival outcomes and improved quality of life for a broad range of patients.
This improves survival outcomes in cardiac arrest cases.
Lesions which undergo curative resection have demonstrated 5-year survival outcomes now exceeding 50%.
Radical surgeries have yielded place to more conservative surgery with the very important objective of quality of life, conserving function and organ without compromising overall survival outcomes.
Multiple retrospective analyses have demonstrated that overall survival and disease-free survival outcomes are similar between radical prostatectomy, external beam radiation therapy, and brachytherapy.
Moreover, there are classes of patients with unconfirmed infection, or for whom cultures are negative yet who develop similar symptoms, rates of organ failure and survival outcomes as do those in patients in whom infection is confirmed.
Prior to 1993, when the IPI was developed, the primary consideration in assessing prognosis was the Ann Arbor stage alone, but this was increasingly found to be an inadequate means of predicting survival outcomes, and so other factors were studied.
In contrast to the conclusions reached by the University of Wisconsin-Madison (WNPRC) study, a 2012 National Institute on Aging (NIA) study published in the journal Nature, concluded that a calorie restriction regimen did not improve survival outcomes whether implemented in young or older age rhesus monkeys.