suppressor mutation

Suppressor mutations are useful for identifying new genetic sites which affect a biological process of interest.

Another possibility for mutation correction is the use of a suppressor mutation.

In addition to the reading frame, Crick also used suppressor mutations to determine codon size.

Unfortunately, no study has yet investigated explicitly the decay function of proteins that carry such a suppressor mutation.

Intragenic suppression results from suppressor mutations that occur in the same gene as the original mutation.

A suppressor screen is used to identify suppressor mutations which alleviate or revert the phenotype of the original mutation.

Alan Garen is geneticist, who co-discovered suppressor mutations for tRNA.

A suppressor mutation is a second mutation that alleviates or reverts the phenotypic effects of an already existing mutation.

Thus, amber mutants are an entire class of virus mutants that can grow in bacteria that contain amber suppressor mutations.

Suppressor mutations can be described as second mutations at a site on the chromosome distinct from the mutation under study, which suppress the phenotype of the original mutation.

This deceleration may be attributed to suppressor mutations that stabilize parts of the protein against further mutations [ 53 ] , which in essence is a form of compensation.

In microbial genetics, a revertant is a mutant that has reverted to its former genotype or to the original phenotype by means of a suppressor mutation, or else by compensatory mutation somewhere in the gene (second site reversion).

However, based on the results from yeast mutant screens that identify second site suppressor mutations in M1 and M2 segments in Kir2.1, Minor et al. [ 5 ] proposed Alignment B in which the Kir sequences of Fig.