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Matthew Boulton, in 1770, claimed that Birmingham's superiority as a manufacturing town was largely due to the "superactivity" of the people, and the "mechanical contrivances and extensive apparatus which we are possess'd of".
A few rare genetic disorders, including familial juvenile hyperuricemic nephropathy, medullary cystic kidney disease, phosphoribosylpyrophosphate synthetase superactivity, and hypoxanthine-guanine phosphoribosyltransferase deficiency as seen in Lesch-Nyhan syndrome, are complicated by gout.
Rara Machine, one of the Haitian community's newest bands, has picked up New York's freneticism; most of its members have spent the major part of their lives here, and the music, with its jazz and rock influences and its speeded-up and nervous superactivity, sounds cosmopolitan.