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Reaction with sulphite to a sulphonic acid and its monoxide derivative.
The smoke screen device consisted of a sulphonic acid reservoir located over the exhaust pipe.
In general they are diazo and sulphonic acid derivatives of benzene and naphthol.
First, there is the widely used practice of introducing sulphonic acid residues into dyestuffs to improve their solubility.
Nicholson then observed that introducing one or more sulphonic acid residues (Nicholson's blue,5 ) greatly improved the handling properties of these colouring agents.
Thus, they are prone to oxidization to sulphonic acids as well as reduction via sulphenic acids (+2) to thiols.
The results obtained indicate that inhibition of its action induced a significant reduction of colonic inflammation in the chronic model of colitis induced by trinitrobenzene sulphonic acid.
These organic compounds include: hydrocarbons, carboxylic acids, alcohols, ketones, aldehydes, amines, amides, sulphonic acids, phosphonic acidss, amino acids, nitrogenous bases, etc.
"Concurrent infection with Schistosoma mansoni attenuates inflammation induced changes in colonic morphology, cytokine levels, and smooth muscle contractility of trinitrobenzene sulphonic acid induced colitis in rats".
According to Speakmann the following phenomena can be seen in the stretched woolen fiber: The cystine side chains are subjected to a hydrolysis at the sulphur bridge, where cystine is dissolved into cysteine and a not yet isolated sulphonic acid.
An animal model of colitis, however, has been developed recently using the free radical initiator, 2,2'-azobis(2-amidinopropane) dihydrochloride and trinitrobenzene sulphonic acid, which also induces colitis experimentally and is metabolised to superoxide and hydrogen peroxide by rat colon homogenates or isolated colonocytes.
It can also be produced by alkaline hydrolysis of chlorobenzenes at high temperature and pressure, by conversion of diazonium salts of chlorinated anilines, or by chlorination of phenolsulphonic acids and benzenesulphonic acids followed by removal of the sulphonic acid group.