sulfonyl chloride

The sulfonyl chlorides are of dominant importance in this series.

A practical, general synthesis of sulfonyl chlorides is presented.

In practical terms this is almost always chloride to give the sulfonyl chloride.

The classic approach entails the reaction of sulfonyl chlorides with an amines.

The resulting sulfonyl chlorides are widely used in the detergent industry as a raw material.

The only industrially important sulfonyl chloride is the benzene derivative.

These salts are generated by reduction of sulfonyl chlorides.

This is the first clearly proved preparation of a compound which is both an alcohol and a sulfonyl chloride.

In general sulfonyl chlorides furnish mercaptans as hydride reduction products.

Thioglycolic acid is developed as a new sulfur transfer agent for sulfonyl chloride synthesis.

Sulfonamides are prepared by the reaction of a sulfonyl chloride with ammonia or an amine.

Sulfonic acids react with thionyl chloride to produce sulfonyl chlorides.

For example, chlorination in the presence of water affords the chloromethyl sulfonyl chloride:

In the Reed reaction, sulfur dioxide, chlorine and light convert hydrocarbons to sulfonyl chlorides.

A readily available sulfonyl chloride source is tosyl chloride.

Sulfides are advanced as sulfonyl chloride precursors.

Key words: sulfonyl chlorides, primary and secondary amines, pH–yield profiles, organic synthesis in water, hydrophobic effects.

Similarly, with sulfonyl chlorides, one obtains sulfonamides.

Such sulfonate esters are often prepared by alcoholysis of the sulfonyl chlorides:

Phenylsulfinic acid can be prepared in several ways, most easily through reduction of sulfonyl chlorides with zinc dust or iron.

Highly functionalised sulfonamides will be synthesized starting from readily available aryl sulfonyl chlorides (Figure 2).

Sulfonyl chlorides have also been prepared from the direct reaction of the corresponding diazonium salt with thionyl chloride.

The Reed reaction is a chemical reaction that utilizes light to oxidize hydrocarbons to sulfonyl chlorides.

Finally, the least one attacks another chlorine molecule to produce a sulfonyl chloride and a new chlorine atom which continues the reaction chain.

The simplest organic sulfonyl chloride, it is used to make methane sulfonates and to generate the elusive molecule sulfene.