subcapsular sinus

Under the fibrous tissue are located peritrabecular and subcapsular sinuses.

This lymph enters the subcapsular sinus.

In the lymph node cortex, the subcapsular sinus drains to trabecular sinuses.

The subcapsular sinus drains into trabecular sinuses and finally into medullary sinuses.

Thus, the subcapsular sinus is a sinus immediately deep to the capsule, and its endothelium is continuous with that of the afferent lymph vessel.

The subcapsular sinus has clinical importance as it is the most likely location where the earliest manifestations of a metastatic carcinoma in a lymph node would be found.

Lymph circulates to the lymph node via afferent lymphatic vessels and drains into the node just beneath the capsule in a space called the subcapsular sinus.

The subcapsular sinus (lymph path, lymph sinus, marginal sinus) is a region within the lymph node immediately deep to the capsule that contains relatively sparse lymphocytes.