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A first microfluidic platform technology reported in literature is based on stimuli-responsive gels.
Although stimuli-responsive drug delivery systems are an effective technique which solves such problems, a special device is necessary in order to apply the stimulus.
Of special interest are stimuli-responsive polymers that respond to pH or temperature changes for the use in targeted delivery.
The resulting stimuli-responsive polymers are being developed as smart materials for controlled drug release, biosensors and for use in bionics.
Microvalves based on stimuli-responsive hydrogels show some advantageous properties such as particle tolerance, no leakage and outstanding pressure resistance.
Smart polymers or stimuli-responsive polymers are high-performance polymers that change according to the environment they are in.
Thermoresponsive polymers belong to the class of stimuli-responsive materials, in contrast to temperature-sensitive (for short, thermosensitive) materials, which change their properties continuously with environmental conditions.
Stimuli-responsive gels (hydrogels, when the swelling agent is an aqueous solution) are a special kind of swellable polymer networks with volume phase transition behaviour.
Stimuli-Responsive Polymers (these allow for responsive drug delivery systems and smart surfaces for cell culture and regenerative medicine.)
These monolithic devices consist of an array of thousands of multimodal modulators (actuator pixels) based on stimuli-responsive hydrogels.
Combined with an excellent compatibility with micro fabrication technologies, especially stimuli-responsive hydrogels are of strong increasing interest for microsystems with sensors and actuators.
Regulated drug delivery, or more appropriately called, stimuli-responsive drug delivery, is a concept in which a drug or drugs is/are delivered at an appropriate rate in response to stimuli.
The Intelligent Polymer Research Institute (IPRI) has developed global linkages with research institutions in the USA, Japan, South Korea, China, Ireland, France, New Zealand, Singapore, Thailand and the United Kingdom working on multifunctional, stimuli-responsive materials for various applications.
He also has led and directed the National Science Foundation Research Centers, Industry/University Cooperative Research Center in Coatings (1995-2005) and Materials Research Science and Engineering Center (MRSEC) on Stimuli-Responsive Polymeric Films and Coatings.