sterigmatocystin

Isolation data suggest sterigmatocystin may have been produced by one or both of these species.

The occurrence of sterigmatocystin in raw materials and foods has not been reported often.

The natural occurrence of sterigmatocystin (S) in in-shell pecans is reported.

The toxic effects of sterigmatocystin are much the same as those of aflatoxin B1.

There appear to be no reports about the stability of sterigmatocystin, other than in solution, where it is similar to the aflatoxins.

A number of closely related compounds such as o-methyl sterigmatocystin are known, and some may also occur naturally.

It accumulates very large amounts of sterigmatocystin, 3-O-methylsterigmatocystin and aflatoxin B1.

If this is the true situation it would be justified to consider sterigmatocystin as no more than a risk to consumers in special or unusual circumstances.

No country has legislation for sterigmatocystin.

It has been suggested that sterigmatocystin is about 1/10 as potent a carcinogen as aflatoxin B1.

Relatively high levels of sterigmatocystin have been formed in bread, cured ham and salami after inoculation with A. versicolor.

Sterigmatocystin itself is toxic and is a precursor to another toxic metabolite, aflatoxin.

There is one report that phosphine gas significantly depresses the formation of sterigmatocystin when cereals are inoculated with A. versicolor.

Incidence of A. flavus and A. glaucus, species known to produce sterigmatocystin under laboratory conditions, was high (43 and 35%, respectively).

Methods for extraction of sterigmatocystin have been commonly based on a mixture of acetonitrile and 4% aqueous potassium chloride.

Penicillium inflatum is an anamorph species of the genus of Penicillium which produces sterigmatocystin.

The acute toxicity, carcinogenicity, and metabolism of sterigmatocystin has been compared with those for aflatoxin and several other hepatotoxic mycotoxins.

These strains were then resistant also towards compounds with a double furan system (aflatoxins B1, B2, G1, G2, and sterigmatocystin).

Sterigmatocystin forms pale yellow needles and that are readily soluble in methanol, ethanol, acetonitrile, benzene, and chloroform.

Sterigmatocystin reacts with a hot solution of potassium hydroxide and ethanol and is easily methylated by methyl iodide.

It has a characteristic musty odor associated with moldy homes and is a major producer of the hepatotoxic and carcinogenic mycotoxin sterigmatocystin.

The only exception is sterigmatocystin, which can account for up to 1% of the total biomass of A. versicolor under optimal conditions (e.g. a of 1).

For example, a functional ST gene cluster that produces sterigmatocystin was found in Podospora anserina and originally derived from Aspergillus.

Thus, the two substrates of this enzyme are S-adenosyl methionine and 6-demethylsterigmatocystin, whereas its two products are S-adenosylhomocysteine and sterigmatocystin.

Bond cleavage and rearrangement of NLX to form AOH may be similar to aflatoxin B1 formation from sterigmatocystin.