The nucleolus disintegrates and the centrosomes move to opposite poles of the cell, forming a bridge of spindle fibers.
The centrosome acts as the "reel" that draws in the spindle fibers or "fishing line".
Prophase is the initial phase when spindle fibers appear that function to move the chromosomes toward opposite poles.
The chromosomes move to opposite poles during anaphase and remain attached to the spindle fibers by their centromeres.
During the final phase of mitosis, telophase, the furrow forms an intercellular bridge using mitotic spindle fibers.
During metaphase, the chromosomes are pulled by microtubules called spindle fibers into place.
The spindle fibers begin to disappear, and a nuclear membrane forms around each set of chromosomes.
Centromere: Used during cell division as the attachment point for the spindle fibers.
Centrioles move to the polar regions and arrange spindle fibers for the second meiotic division.
The spindle fibers either form within the membrane, or penetrate it without tearing it apart.